2012 Adverse Reactions

“MediciNova asthma drug fails trial; shares crash.”
Reuters. 24 May 2012

“Bayer’s Nexavar fails in another lung cancer study.”
PM Live. 22 May 2012.

“FDA staff shoots down Pfizer rare disease drug.”
Reuters. 22 May 2012.

“Zithromax (azithromycin): FDA Statement on risk of cardiovascular death"
FDA Medwatch. 17 May 2012.

“Popular Antibiotic May Raise Risk of Sudden Death”
New York Times. 16 May 2012.

“IOM calls for more thorough safety monitoring of drugs.”
AmedNews.com. 14 May 2012.

 “MedWatch April 2012 Safety Labeling Changes. This posting includes 43 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE INSERT.”
FDA Medwatch. 14 May 2012.

“Promising USF drug falls short in trials.”
Tampa Tribune. 11 May 2012.

“Gilead’s Quad Pill Raises Kidney Questions, FDA Says.”
Bloomberg. 9 May 2012.

“Merck KGaA's Erbitux fails in colon cancer study”
Reuters. 9 May 2012.

“FDA revisits safety of Arena Pharma's diet pill.”
Bloomberg. 8 May 2012.

“Failure Of Roche HDL Booster Is Bad News For Merck And Eli Lilly”
Forbes. 7 May 2012.

“Roche stops heart drug trial as data disappoints”
Chicago Tribune. 7 May 2012.

“Pfizer Drug Lyrica Fails in Phase 3 Study In Patients With Diabetic Peripheral Neuropathy”
A Sweet Life. 6 May 2012.,

“Ritalin use for ADHD soars fourfold as child psychologists warn of untested drug cocktails.”
The Observer. 6 May 2012.

“Pfizer's Lyrica falls short in two pain studies.”
Reuters. 4 May 2012.

“FDA staff question side effects of Regeneron gout drug.”
Reuters. 4 May 2012.

“Targacept’s drug pipeline must fill gap left by lead drug’s phase 3 failure”
Med City News. 3 May 2012.

“Aveo says cancer drug not better than existing therapy.”
Reuters. 2 May 2012.

“For Back Pain, Steroid Shots No More Effective Than Placebo”
New York Times. 27 April 2012.

“Canadian Drug Regulator Issues Warning About the Diabetic Drug ACTOS”
Salient News. 24 April 2012.

“Galena's Breast Cancer Vaccine Doomed to Fail”
The Street. 24 April 2012.

“Cancer link claimed in ovary fertility drugs”
The Guardian. 24 April 2012.

“Spectrum Could Sink In Wake Of Trial Failures.”
Seeking Alpha. 22 April 2012.

“New warnings on Novartis MS pill in Europe and U.S”
Reuters. 20 April 2012.

“Pancreatitis Forces Halt to HCV Drug Trial”
MedPage Today. 19 April 2012.

“Group asks for withdrawal of Victoza diabetes drug.”
Reuters. 19 April 2012.

“Spectrum Could Sink On Aqaziquone Failure.”
Seeking Alpha. 18 April 2012

“Value of Metformin, Insulin Combo for Type 2 Diabetes Questioned. Danish analysis suggests that long-term benefit for patients is unclear”
HealthDay. 17 April 2012.

“Bayer Said to Pay $110 Million in Yaz Birth-Control Cases.”
Bloomberg. 13 April 2012.

“Merck’s Baldness Drug Linked to Sex Concerns After Use”
Business Week. 13 April 2012

“FDA MedWatch - Monthly Safety Labeling Changes March 2012. The MedWatch March 2012 Safety Labeling Changes posting includes 39 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE INSERT. The following drugs had modifications to the BOXED WARNINGS, CONTRAINDICATIONS and WARNINGS sections...”
FDA Medwatch. 12 April 2012.

“Bayer Birth-Control Pill May Boost Risks for Blood Clots.”
Bloomberg. 11 April 2012.

“U.S. adds more on clot risk to some birth control pills.”
Reuters. 10 April 2012.

“Birth Control Pills Containing Drospirenone: Label Change-Products may be associated with a higher risk for blood clots”
FDA Medwatch. 10 April 2012.

“Spectrum says bladder cancer drug fails, buys Allos.”
Reuters. 5 April 2012.

“FDA staff focus on safety of Astellas bladder drug.”
Reuters. 3 April 2012.

“Keryx shares plunge on clinical trial failure”
Bloomberg Business Week. 2 April 2012.

“Uncertainty looms over Keryx, Aeterna cancer drug”
Chicago Tribune. 2 April 2012.

“Shire hit by bowel drug study failure”
Reuters. 30 March 2012.

“Pfizer Judge Certifies Class Action Over Celebrex, Bextra.”
Bloomberg. 29 March 2012.

“Swine flu jab linked to narcolepsy”
The Independent. 29 March 2012.

“No Answers Yet From Key Trial Of Merck Cholesterol Drugs”
Forbes. 28 March 2012.

“Celexa (citalopram hydrobromide) - Drug Safety Communication: Revised Recommendations, Potential Risk of Abnormal Heart Rhythms”
FDA Medwatch. 28 March 2012.

“UK health officials probe possible flu jab link to narcolepsy in children. Investigation centres on Pandemrix vaccine used extensively during 'swine flu' pandemic in 2009/10.”
The Guardian. 28 March 2012.

“J&J Duped Arkansas Doctors Over Risperdal, Lawyer Tells Jury.”
Bloomberg. 27 March 2012.

“Heart-damaging Side Effects of Cancer Drugs Under-reported in Published Studies, Stanford researchers say”
Health News Digest. 27 March 2012.

“Texas, Johnson & Johnson heading back to court.”
Reuters. 25 March 2012.

“Antidepressants give drugmakers the blues”
Dawn.com. 25 March 2012.

“Merck blood clot drug in limbo after mixed results.”
Reuters. 24 March 2012.

“How the FDA forgot the evidence: the case of donepezil 23 mg.”
BMJ 22 March 2012; 344 doi: 10.1136/bmj.e1086.

“New Alzheimer's pill more likely to cause misery, medical experts say.”
LA Times. 22 March 2012.

“AstraZeneca antidepressant is dumped after trial failures.”
The Independent. 21 March 2012.

“Depressing Clinical Trial News.”
Daily Finance. 20 March 2012.

“Targacept drug halted after failure in clinical trials”
Winston-Salem Journal. 20 March 2012.

“MedWatch February 2012 Safety Labeling Changes. This posting includes 65 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE INSERT.”
MedWatch. 15 March 2012.

Varespladib phase 3 ACS trial halted early”
The Heart. 15 March 2012.

AstraZeneca takes legal action to delay generic quetiapine in US.”
BMJ 15 March 2012; 344 doi: 10.1136/bmj.e2099.

“Why Miracle Drugs Are (Almost) Never as Miraculous As They Seem.”
The Atlantic. 13 March 2012.

“J&J's Drug Settlement for $1 Billion Is Rejected”
Wall Street Journal. 9 March 2012.

“Experimental pain drugs linked with joint failure and bone deterioration. Drugmakers once touted nerve growth factor inhibitors as a potential breakthrough.”
New York Daily News. 9 March 2012. 

“Takeda Hid Actos Adverse Effects From Regulators, Suit Says.”
Bloomberg. 7 March 2012. 

“Death magnifies Pradaxa hemorrhage concerns.”
Reuters. 6 March 2012. 

“Novartis’s Gilenya Loses Market Share After Safety Review.”
Bloomberg.com. 6 March 2012.

“Actos Litigation Moves Forward. Scientists recently linked the blockbuster diabetes drug Actos to bladder cancer. Actos' maker insists that the benefits of the drug outweigh the risks, but bladder cancer sufferers disagree.”
Digital Journal. 5 March 2012.

“The Diabetes Dilemma for Statin Users"
New York Times., 5 March 2012.

“Prescription Meds Can Put on Unwanted Pounds. They include drugs for diabetes, mood disorders and other chronic conditions."
Healthday. 2 March 2012.

“Statins and HIV or Hepatitis C Drugs: Drug Safety Communication – Interaction Increases Risk of Muscle Injury”
FDA Medwatch. 1 March 2012.

“FDA adds diabetes, memory loss warnings to statins.”
Reuters. 29 February 2012.

“Sleeping pills increase risk of death, study suggests. Doctors call for rethink after large study finds prescribed pills could be associated with up to 0.5m extra deaths a year in US.”
The Guardian. 27 February 2012.

“Drugmakers continue search for diet pill despite failures.”
LubbockOnline. 25 February 2012.

“Antipsychotics death risk charted in dementia patients”
BBC News. 24 February 2012.

“Agency is under fire for refusing to supply details of sudden deaths after first dose of multiple sclerosis drug”
BMJ 23 February 2012; 344 doi: 10.1136/bmj.e1360

“Alzheimer’s Drugs Harmful? The researcher who helped develop an Alzheimer’s treatment now in clinical trials warns that the compound may actually impair memory.”
The Scientist. 20 February 2012.

“HIV drug tenofovir increases risk of kidney damage”
SF Gate. 18 February 2012.

“Novartis to Add Warnings to Rasilez Blood-Pressure Drug"
Bloomberg. 17 February 2012.

“Cause of deaths unclear in Actelion drug trial”
Chicago Tribune. 14 February 2012.

“The MedWatch January 2012 Safety Labeling Changes posting includes 63 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE INSERT.”
FDA Medwatch. 13 February 2012.

“Appetite suppressant was probably responsible for 1300 deaths, study shows.”
BMJ 2012; 344 doi: 10.1136/bmj.e996 (Published 9 February 2012)

 “Panel Nixes AML Indication for Dacogen.”
Medpage Today. 9 February 2012.

“New Antibiotic for Bladder Infection Disappoints in Trial.”
Healthday. 8 February 2012.

“Certain Cancer Drugs May Have Fatal Side Effects: Analysis.”
US News Health. 8 February 2012.

“FDA Issues Warning on Acid Reflux Drugs.”
Medpage Today. 8 February 2012.

“Bridport youngster in marrow transplant after cancer drug trial failure.”
Dorset Echo. 8 February 2012.

“Pfizer’s Breast-Cancer Drug Worsens Bone Loss in Older Women.”
Bloomberg. 7 February 2012.

“US Drug Watchdog Expands Their Initiative for Diabetics Who Used the Diabetes Drug Actos and Then Developed Bladder Cancer with Focus on Compensation & the Best Lawyers.”
PRWeb. 6 February 2012.

“Certain Cancer Drugs May Have Fatal Side Effects”
Healthday. 6 February 2012.

“Cancer-Deterring Drug Found to Harm Bones.”
New York Times. 6 February 2012.

“Type 1 Diabetes Treatment Disappoints in Trial. Vaccine-based approach didn't affect insulin needs or other markers.”
Healthday. 1 February 2012.

“Heartburn Drugs May Raise Fracture Risk in Older Women”
Healthday. 31 January 2012.

“Diabetes drugs tied to pancreatic cancer risk”
Reuters. 31 January 2012.

“Infinity craters after lead drug flunks PhII cancer study.”
Fierce Biotech. 27 January 2012.

 “Novartis’s Gilenya Pill Reviewed by EU, U.S. After 11 Deaths”
Bloomberg Business Week. 22 January 2012.

“AstraZeneca May Rethink Aversion to Big Deals After Setbacks”
Bloomberg Business Week. 22 January 2012.

“Thousands of women could be at risk from 'silent Thalidomide'. A drug intended to prevent miscarriage is blamed for causing cancer in the daughters – and possibly even granddaughters – of women who took it decades ago.”
Independent on Sunday. 22 January 2012.

“Bristol, AstraZeneca Diabetes Drug Fails to Win FDA Backing.”
Bloomberg Business Week. 19 January 2012.

“Merck to pay at least $21.8 million to settle Vioxx lawsuits in Canada”
Canadian Business. 19 January 2012.

“Bristol, AstraZeneca Diabetes Drug Fails to Win FDA Backing.”
Bloomberg Business Week. 19 January 2012.

“Pfizer, Medivation End Alzheimer Drug’s Work After Failure.”
Bloomberg Business Week. 19 January 2012.

 “Roche Flu Drug’s Effectiveness Is Unproven, Researchers Say”
Bloomberg Business week. 19 January 2012.

“Melanoma Drug's Link to Other Skin Cancers Identified. New study suggests ways around the risk for patients
HealthDay. 18 January 2012.

“Pfizer, Medivation End Drug Development Deal”
Sci-Tech Today. 18 January 2012.

“Big Pharma Routinely Suppresses Data from Clinical Trials—but FDA Approves these Dangerous Drugs Anyway!”
ANH. 17 January 2012.

“Side effects and effectiveness of 'wonder-drug' Tamiflu under the microscope as Department of Health faces awkward questions over mass prescriptions”
Daily Mail, 17 January 2012

“Antidepressant Use Linked to Increased Pulmonary Hypertension Risk in
Infants.”
New York Times. 13 January 2012.

“Seattle Genetics Lymphoma Drug Gets Boxed Warning on Brain Infection Risk.”
Bloomberg. 13 January 2012.

“Adcetris (brentuximab vedotin): Drug Safety Communication.”
FDA. 13 January 2012.

“The MedWatch December 2011 Safety Labeling Changes posting includes 40 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE INSERT.”
FDA Medwatch. 12 January 2012.

“Boehringer’s Pradaxa Increases Risk of Heart Attack, Study Shows.”
Bloomberg Business Week. 10 January 2012.

“Statins Tied to Lung Damage in Smokers.”
MedPageToday. 6 January 2012.